The research endeavors focus on the investigation of inflammatory and immune-related processes, with particular interest in the functional/modulatory role of histamine and its receptors³ in human (patho)physiology, including autoimmune and inflammatory diseases, allergic responses and drug hypersensitivity reactions. Pharmacologically active agents principally targeting the histaminergic system are evaluated for their translational potential in the orchestration of acute and chronic inflammation⁴, antigen tolerance⁵, development⁶ and the adaptive and protective cellular stress response⁷. Notably, the study of histamine started in the early 20th century, yet the identification of the histamine H4 receptor in 2000 and its distribution mainly, but not exclusively in immune cells revived the interest of the international research community in the role of histamine in immunoregulation and inflammation.